Positively Charged Nylon Capsule Filters

Nupore PoreCap® positively charged Nylon capsule filters are absolute retention filters for endotoxin removal and sterilization of liquids.

Positively Charged Nylon Capsule filters are manufactured with a single layer of nylon-66 membrane and available in 0.22µm, 0.45µm and 0.80µm ratings across different sizes ranging from 1" to 10".

These are hydrophilic, autoclavable, heat resistant, non-media migrating and biologically inert filters with wide chemical compatibility, ideal for filtration and sterilization of buffers, organic solvents and injectables.

Membrane Characteristics: These capsule filters incorporate the positively charged Nylon-66 membrane which has a cationic functional group added to the membrane which provides an extra functionality of retaining smaller negatively charged particles such as endotoxins.

APPLICATIONS

  • Endotoxin Removal
  • Filtration of buffers and other non-aqueous solutions
  • Filtration of Aqueous and organic solvents
  • Sterilization of hormonal injectables
Microbial Validation

Validated as per the ASTM F 838-05 requirements for determining bacterial retention of membrane filters used for liquid filtration

FDA Compliant
Construction raw materials meet the requirements as specified by FDA in Title 21 CFR section 177.1520
Biosafety & Extractables
Passes the biologicals tests for Class VI plastics as described in USP. Our filters are thermally bonded to seal the media (& no adhesives are used) to prevent extraction
Integrity Tested
100% integrity tested to assure reliable filtration performance (bubble point & diffusional flow values provided)
Global Manufacturing Standards
Manufacture lot compliance with cGMP requirements
Easy Identification & Tracking

Each filter unit has a unique identification marking which enables quick backtracking

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100% Integrity Tested

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Guaranteed Specification as per Actual Data

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Non Leachable

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Ergonomically Designed & Developed

TECHNICAL SPECIFICATIONS

Positively Charged Nylon Capsule Filters

Materials of Construction
Membrane: Nylon-6,6 (+ve Charged)
Housing: Polypropylene
Core: Polypropylene
End Connections: Polypropylene
Rings: Silicone (Only with 1/4" MNPT)
Operational Parameters
Max Temp 80 °C @ ≤ 2 Kg/cm2
Max Pressure 3.5kg/cm2 @ 25 °C
Autoclavable 1 autoclavable cycles of 30 minutes at 121 °C
Bubble Point:
0.22µm: ≥ 3450 mbar (50 psi) (with water wetted)
0.45µm: ≥ 2268 mbar (30 psi) (with water wetted)
Max Air Diffusion Flow (for 8" & 10″ Capsule):
0.22µm: ≤ 30 mL/min @ 2882 mbar (36 psi)
0.45µm: ≤ 35 mL/min @ 1650 mbar (24 psi)
Microbial Retention:
0.22µm: LRV > 7 for Brevundimonas Diminuta
0.45µm: LRV > 7 for Serratia marcescens
WP Data Tables

 

Effective Filtration Area:
Length: 1″ 2″ 5″ 8″ 10″
Area: 0.025m2 0.05m2 0.10m2 0.20m2 0.60m2

QUALITY ASSURANCE & VALIDATION

All filters are 100% integrity tested and are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP compliant processes.

Microbial Validation

All our Cartridge and Capsule filters are validated as per the ASTM F 838 requirements for determining bacterial retention of  sterilizing grade filters

Certificate of Quality

All our products are delivered along with a Certificate of Quality (CoQ) mentioning the materials of construction and testing & quality parameters

Throughput Studies

We help you select the perfect mix of prefilters and final filters by performing small scale filtration and determining the filtration area to reach your desired throughput

Extractables & Leachables

Our Extractables & Leachables testing study is a highly effective way to quantify and assess risks associated with leachable impurities from filters

Why Choose Us

With our extensive knowledge in membrane filtration and a wide range of products available at every stage of the process, along with our exceptional customer service, we are able to establish ourselves as the preferred partner.

Filtration Products

Extensive Product Portfolio

At Nupore, we offer a wide range of filtration for your process requirements. Use our quick guide to land instantly at the product of your choice

Membranes

Proven Membrane Technology

Our 30 years of experience in Membrane Manufacturing is now trusted by leading Biopharma and Diagnostic experts globally
4-5 weeks global shipping

Fast Shipping

Are longer lead times impacting your processes? Our average lead times range from 3-4 weeks. Contact us to shorten your lead time

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